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ABCD1 Human Gene Knockout Kit (CRISPR)

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SKU
KN206885BN
ABCD1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ABCD1 or NM_000033"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ABCD1
Locus ID 215
Components

KN206885G1, ABCD1 gRNA vector 1 in pCas-Guide CRISPR vector

KN206885G2, ABCD1 gRNA vector 2 in pCas-Guide CRISPR vector

KN206885BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000033
UniProt ID P33897
Synonyms ABC42; ALD; ALDP; AMN
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA100150 ABCD1 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily D member 1 1 kit
$1,657.00
KN206885 ABCD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206885LP ABCD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206885RB ABCD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406885 ABCD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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