CARD12 (NLRC4) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | CARD12 |
| Locus ID | 58484 |
| Components |
KN206757G1, CARD12 gRNA vector 1 in pCas-Guide CRISPR vector KN206757G2, CARD12 gRNA vector 2 in pCas-Guide CRISPR vector KN206757RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001199138, NM_001199139, NM_001302504, NM_021209 |
| UniProt ID | Q9NPP4 |
| Synonyms | AIFEC; CARD12; CLAN; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; IPAF |
| Summary | This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA111767 | NLRC4 CRISPRa kit - CRISPR gene activation of human NLR family CARD domain containing 4 | 1 kit |
$1,657.00
|
|
| KN206757 | NLRC4 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206757BN | NLRC4 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206757LP | NLRC4 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN406757 | NLRC4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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