Occludin (OCLN) Human Gene Knockout Kit (CRISPR)

SKU
KN206468RB
OCLN - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Occludin
Locus ID 100506658
Components

KN206468G1, Occludin gRNA vector 1 in pCas-Guide CRISPR vector

KN206468G2, Occludin gRNA vector 2 in pCas-Guide CRISPR vector

KN206468RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001205254, NM_001205255, NM_002538
UniProt ID Q16625
Synonyms BLCPMG; PPP1R115
Summary This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. provided by RefSeq, Apr 2011
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Other Versions
SKU Description Size Price
GA119306 OCLN CRISPRa kit - CRISPR gene activation of human occludin 1 kit
$1,657.00
KN206468 OCLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206468BN OCLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206468LP OCLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406468 OCLN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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