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Caspase 10 (CASP10) Human Gene Knockout Kit (CRISPR)

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SKU
KN206379LP
CASP10 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Caspase 10 or NM_001206524"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Caspase 10
Locus ID 843
Components

KN206379G1, Caspase 10 gRNA vector 1 in pCas-Guide CRISPR vector

KN206379G2, Caspase 10 gRNA vector 2 in pCas-Guide CRISPR vector

KN206379LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001206524, NM_001206542, NM_001230, NM_001306083, NM_032974, NM_032976, NM_032977
UniProt ID Q92851
Synonyms ALPS2; FLICE2; MCH4
Summary This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Apr 2011
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Other Versions
SKU Description Size Price
GA100596 CASP10 CRISPRa kit - CRISPR gene activation of human caspase 10 1 kit
$1,657.00
KN206379 CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206379BN CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206379RB CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406379 CASP10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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