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Human Caspase 10 (CASP10) activation kit by CRISPRa

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SKU
GA100596
CASP10 CRISPRa kit - CRISPR gene activation of human caspase 10
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA322125 Anti-CASP10 Rabbit Polyclonal Antibody
100 ul
$305.00
RC206379 CASP10 (Myc-DDK-tagged)-Human caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant 1
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Other products for "CASP10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CASP10
Locus ID 843
Components

GA100596G1, Caspase 10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100596G2, Caspase 10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100596G3, Caspase 10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001206524, NM_001206542, NM_001230, NM_001306083, NM_032974, NM_032976, NM_032977
UniProt ID Q92851
Synonyms ALPS2; FLICE2; MCH4
Summary This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Apr 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN206379 CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206379BN CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206379LP CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206379RB CASP10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406379 CASP10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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