OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

MTREX Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN206080LP
SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA332776 Rabbit anti-MTR4 Polyclonal Antibody
100 ul
$410.00
RC206080 SKIV2L2 (Myc-DDK-tagged)-Human superkiller viralicidic activity 2-like 2 (S. cerevisiae) (SKIV2L2)
10 ug
$907.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "MTREX or NM_015360"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol MTREX
Locus ID 23517
Components

KN206080G1, MTREX gRNA vector 1 in pCas-Guide CRISPR vector

KN206080G2, MTREX gRNA vector 2 in pCas-Guide CRISPR vector

KN206080LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_015360
UniProt ID P42285
Synonyms Dob1; fSAP118; KIAA0052; Mtr4
Summary Component of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA (PubMed:17412707, PubMed:29107693). May be involved in pre-mRNA splicing.UniProtKB/Swiss-Prot Function
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA108361 MTREX CRISPRa kit - CRISPR gene activation of human Mtr4 exosome RNA helicase 1 kit
$1,657.00
KN206080 SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206080BN SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206080RB SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406080 SKIV2L2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products