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Human MTREX activation kit by CRISPRa

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SKU
GA108361
MTREX CRISPRa kit - CRISPR gene activation of human Mtr4 exosome RNA helicase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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Other products for "MTREX"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MTREX
Locus ID 23517
Components

GA108361G1, MTREX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108361G2, MTREX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108361G3, MTREX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_015360
UniProt ID P42285
Synonyms Dob1; fSAP118; KIAA0052; Mtr4
Summary Component of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA (PubMed:17412707, PubMed:29107693). May be involved in pre-mRNA splicing.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN206080 SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206080BN SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206080LP SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206080RB SKIV2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406080 SKIV2L2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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