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ERp57 (PDIA3) Human Gene Knockout Kit (CRISPR)

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SKU
KN205940LP
PDIA3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ERp57 or NM_005313"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol ERp57
Locus ID 2923
Components

KN205940G1, ERp57 gRNA vector 1 in pCas-Guide CRISPR vector

KN205940G2, ERp57 gRNA vector 2 in pCas-Guide CRISPR vector

KN205940LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_005313
UniProt ID P30101
Synonyms ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC
Summary This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. provided by RefSeq, Dec 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA101978 PDIA3 CRISPRa kit - CRISPR gene activation of human protein disulfide isomerase family A member 3 1 kit
$1,657.00
KN205940 PDIA3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205940BN PDIA3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205940RB PDIA3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405940 PDIA3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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