Myosin Light Chain 2 (MYL2) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | Myosin Light Chain 2 |
| Locus ID | 4633 |
| Components |
KN205932G1, Myosin Light Chain 2 gRNA vector 1 in pCas-Guide CRISPR vector KN205932G2, Myosin Light Chain 2 gRNA vector 2 in pCas-Guide CRISPR vector KN205932LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_000432 |
| UniProt ID | P10916 |
| Synonyms | CMH10; MLC-2s/v; MLC2 |
| Summary | Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
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| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA103073 | MYL2 CRISPRa kit - CRISPR gene activation of human myosin light chain 2 | 1 kit |
$1,657.00
|
|
| KN205932 | MYL2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN205932BN | MYL2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN205932RB | MYL2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN405932 | MYL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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