HMG1 (HMGB1) Human Gene Knockout Kit (CRISPR)

SKU
KN205918RB
HMGB1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol HMG1
Locus ID 3146
Components

KN205918G1, HMG1 gRNA vector 1 in pCas-Guide CRISPR vector

KN205918G2, HMG1 gRNA vector 2 in pCas-Guide CRISPR vector

KN205918RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001313892, NM_001313893, NM_002128, NM_001363661, NM_001370339, NM_001370340, NM_001370341
UniProt ID P09429
Synonyms HMG1; HMG3; SBP-1
Summary This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
GA102145 HMGB1 CRISPRa kit - CRISPR gene activation of human high mobility group box 1 1 kit
$1,657.00
KN205918 HMGB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205918BN HMGB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205918LP HMGB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405918 HMGB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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