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ABCG2 Human Gene Knockout Kit (CRISPR)

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SKU
KN205640BN
ABCG2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ABCG2 or NM_001257386"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ABCG2
Locus ID 9429
Components

KN205640G1, ABCG2 gRNA vector 1 in pCas-Guide CRISPR vector

KN205640G2, ABCG2 gRNA vector 2 in pCas-Guide CRISPR vector

KN205640BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001257386, NM_004827, NM_001348985, NM_001348986, NM_001348987, NM_001348988, NM_001348989
UniProt ID Q9UNQ0
Synonyms ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR1; UAQTL1
Summary The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2012
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Documents
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Other Versions
SKU Description Size Price
GA106296 ABCG2 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily G member 2 (Junior blood group) 1 kit
$1,657.00
KN205640 ABCG2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205640LP ABCG2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205640RB ABCG2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405640 ABCG2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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