COMMD1 Human Gene Knockout Kit (CRISPR)

CAT#: KN205614BN

COMMD1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: COMMD1
• Locus ID: 150684
• Components:

  KN205614G1, COMMD1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205614G2, COMMD1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205614BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001321781, NM_001321782, NM_152516
• UniProt ID: Q8N668
• Synonyms: C2orf5; MURR1
• Summary: COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009]