ACTRT1 Human Gene Knockout Kit (CRISPR)

CAT#: KN205402BN

ACTRT1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: ACTRT1
• Locus ID: 139741
• Components:

  KN205402G1, ACTRT1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205402G2, ACTRT1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205402BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_138289
• UniProt ID: Q8TDG2
• Synonyms: AIP1; ARIP1; ARPT1; HSD27
• Summary: This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]