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PKC iota (PRKCI) Human Gene Knockout Kit (CRISPR)

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SKU
KN205379RB
PRKCI - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "PKC iota or NM_002740"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PKC iota
Locus ID 5584
Components

KN205379G1, PKC iota gRNA vector 1 in pCas-Guide CRISPR vector

KN205379G2, PKC iota gRNA vector 2 in pCas-Guide CRISPR vector

KN205379RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002740
UniProt ID P41743
Synonyms DXS1179E; nPKC-iota; PKCI
Summary This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103774 PRKCI CRISPRa kit - CRISPR gene activation of human protein kinase C iota 1 kit
$1,657.00
KN205379 PRKCI - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205379BN PRKCI - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205379LP PRKCI - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405379 PRKCI - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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