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MCSF Receptor (CSF1R) Human Gene Knockout Kit (CRISPR)

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SKU
KN205288BN
CSF1R - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "MCSF Receptor or NM_001288705"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol MCSF Receptor
Locus ID 1436
Components

KN205288G1, MCSF Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN205288G2, MCSF Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN205288BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001288705, NM_005211, NR_109969, NM_001349736
UniProt ID P07333
Synonyms C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Summary The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA101010 CSF1R CRISPRa kit - CRISPR gene activation of human colony stimulating factor 1 receptor 1 kit
$1,657.00
KN205288 CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205288LP CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205288RB CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405288 CSF1R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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