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Human MCSF Receptor (CSF1R) activation kit by CRISPRa

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SKU
GA101010
CSF1R CRISPRa kit - CRISPR gene activation of human colony stimulating factor 1 receptor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA300025 MCSF Receptor (CSF1R) Antibody (C-term)
400 ul
$645.00
RC205288 CSF1R (Myc-DDK-tagged)-Human colony stimulating factor 1 receptor (CSF1R)
10 ug
$1,335.00

Other products for "CSF1R"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CSF1R
Locus ID 1436
Components

GA101010G1, MCSF Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101010G2, MCSF Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101010G3, MCSF Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001288705, NM_005211, NR_109969, NM_001349736
UniProt ID P07333
Synonyms C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Summary The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN205288 CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205288BN CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205288LP CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205288RB CSF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405288 CSF1R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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