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PAK5 Human Gene Knockout Kit (CRISPR)

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SKU
KN205255RB
PAK7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PAK5 or NM_020341"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PAK5
Locus ID 57144
Components

KN205255G1, PAK5 gRNA vector 1 in pCas-Guide CRISPR vector

KN205255G2, PAK5 gRNA vector 2 in pCas-Guide CRISPR vector

KN205255RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_020341, NM_177990
UniProt ID Q9P286
Synonyms PAK5
Summary The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA111404 PAK5 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 5 1 kit
$1,657.00
KN205255 PAK5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205255BN PAK7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205255LP PAK7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405255 PAK5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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