Endothelin B Receptor (EDNRB) Human Gene Knockout Kit (CRISPR)

SKU
KN204899LP
EDNRB - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Endothelin B Receptor
Locus ID 1910
Components

KN204899G1, Endothelin B Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN204899G2, Endothelin B Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN204899LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000115, NM_001122659, NM_001201397, NM_003991
UniProt ID P24530
Synonyms ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A
Summary The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. provided by RefSeq, Oct 2016
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Other Versions
SKU Description Size Price
GA101331 EDNRB CRISPRa kit - CRISPR gene activation of human endothelin receptor type B 1 kit
$1,657.00
KN204899 EDNRB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204899BN EDNRB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204899RB EDNRB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404899 EDNRB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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