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XRCC4 Human Gene Knockout Kit (CRISPR)

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SKU
KN204783BN
XRCC4 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol XRCC4
Locus ID 7518
Components

KN204783G1, XRCC4 gRNA vector 1 in pCas-Guide CRISPR vector

KN204783G2, XRCC4 gRNA vector 2 in pCas-Guide CRISPR vector

KN204783BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001318012, NM_001318013, NM_003401, NM_022406, NM_022550
UniProt ID Q13426
Synonyms SSMED
Summary The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. provided by RefSeq, Oct 2019
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Resources
Other Versions
SKU Description Size Price
GA105176 XRCC4 CRISPRa kit - CRISPR gene activation of human X-ray repair cross complementing 4 1 kit
$1,657.00
KN204783 XRCC4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204783LP XRCC4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204783RB XRCC4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404783 XRCC4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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