PAH Human Gene Knockout Kit (CRISPR)

SKU
KN204694RB
PAH - human gene knockout kit via CRISPR, HDR mediated
$1,657.00
4 Weeks*
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PAH
Locus ID 5053
Components

KN204694G1, PAH gRNA vector 1 in pCas-Guide CRISPR vector

KN204694G2, PAH gRNA vector 2 in pCas-Guide CRISPR vector

KN204694RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000277, NM_001354304
UniProt ID P00439
Synonyms PH; PKU; PKU1
Summary This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]
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More linear donor DNA can be ordered separately

Cat# KN204694RBD
Description 10 ug linear donor DNA for KN204694RB kit
Price $515/€515
If you want to order 20ug, please order quantity of 2 for KN204694RBD
If you want to order 50ug, please order quantity of 5 for KN204694RBD

Other selection marker is available for donor DNA.
Please contact techsupport@origene.com for a custom quote.

different donor dna img
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Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.