PTOP (ACD) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | PTOP |
| Locus ID | 65057 |
| Components |
KN204381G1, PTOP gRNA vector 1 in pCas-Guide CRISPR vector KN204381G2, PTOP gRNA vector 2 in pCas-Guide CRISPR vector KN204381LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001082486, NM_001082487, NM_022914 |
| UniProt ID | Q96AP0 |
| Synonyms | PIP1; PTOP; TINT1; TPP1 |
| Summary | This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA112225 | ACD CRISPRa kit - CRISPR gene activation of human ACD shelterin complex subunit and telomerase recruitment factor | 1 kit |
$1,657.00
|
|
| KN204381 | ACD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN204381BN | ACD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN204381RB | ACD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN404381 | ACD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.