PTOP (ACD) Human Gene Knockout Kit (CRISPR)

SKU
KN204381LP
ACD - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol PTOP
Locus ID 65057
Components

KN204381G1, PTOP gRNA vector 1 in pCas-Guide CRISPR vector

KN204381G2, PTOP gRNA vector 2 in pCas-Guide CRISPR vector

KN204381LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001082486, NM_001082487, NM_022914
UniProt ID Q96AP0
Synonyms PIP1; PTOP; TINT1; TPP1
Summary This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA112225 ACD CRISPRa kit - CRISPR gene activation of human ACD shelterin complex subunit and telomerase recruitment factor 1 kit
$1,657.00
KN204381 ACD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204381BN ACD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204381RB ACD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404381 ACD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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