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TIFA Human Gene Knockout Kit (CRISPR)

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SKU
KN204357RB
TIFA - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "TIFA or NM_052864"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol TIFA
Locus ID 92610
Components

KN204357G1, TIFA gRNA vector 1 in pCas-Guide CRISPR vector

KN204357G2, TIFA gRNA vector 2 in pCas-Guide CRISPR vector

KN204357RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_052864
UniProt ID Q96CG3
Synonyms T2BP; T6BP; TIFAA
Summary This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. provided by RefSeq, Jun 2018
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Documents
Resources
Other Versions
SKU Description Size Price
GA114228 TIFA CRISPRa kit - CRISPR gene activation of human TRAF interacting protein with forkhead associated domain 1 kit
$1,657.00
KN204357 TIFA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204357BN TIFA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204357LP TIFA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404357 TIFA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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