Human TIFA activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | TIFA |
| Locus ID | 92610 |
| Components |
GA114228G1, TIFA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114228G2, TIFA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114228G3, TIFA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_052864 |
| UniProt ID | Q96CG3 |
| Synonyms | T2BP; T6BP; TIFAA |
| Summary | This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. provided by RefSeq, Jun 2018 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN204357 | TIFA - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN204357BN | TIFA - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN204357LP | TIFA - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN204357RB | TIFA - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN404357 | TIFA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.