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MALT1 Human Gene Knockout Kit (CRISPR)

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SKU
KN204322RB
MALT1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "MALT1 or NM_006785"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol MALT1
Locus ID 10892
Components

KN204322G1, MALT1 gRNA vector 1 in pCas-Guide CRISPR vector

KN204322G2, MALT1 gRNA vector 2 in pCas-Guide CRISPR vector

KN204322RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_006785, NM_173844
UniProt ID Q9UDY8
Synonyms IMD12; MLT; MLT1
Summary This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus BIRC3(API2)-MALT1, and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. provided by RefSeq, May 2018
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Documents
Resources
Other Versions
SKU Description Size Price
GA107463 MALT1 CRISPRa kit - CRISPR gene activation of human MALT1 paracaspase 1 kit
$1,657.00
KN204322 MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204322BN MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204322LP MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404322 MALT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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