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Human MALT1 activation kit by CRISPRa

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SKU
GA107463
MALT1 CRISPRa kit - CRISPR gene activation of human MALT1 paracaspase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC214639 MALT1 (Myc-DDK-tagged)-Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 1
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Other products for "MALT1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MALT1
Locus ID 10892
Components

GA107463G1, MALT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107463G2, MALT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107463G3, MALT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006785, NM_173844
UniProt ID Q9UDY8
Synonyms IMD12; MLT; MLT1
Summary This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus BIRC3(API2)-MALT1, and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. provided by RefSeq, May 2018
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Documents
Resources
Other Versions
SKU Description Size Price
KN204322 MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204322BN MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204322LP MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204322RB MALT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404322 MALT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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