MFSD2A Human Gene Knockout Kit (CRISPR)

SKU KN204264BN

MFSD2A - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: MFSD2A
• Locus ID: 84879
• Components:

  KN204264G1, MFSD2A gRNA vector 1 in pCas-Guide CRISPR vector

  KN204264G2, MFSD2A gRNA vector 2 in pCas-Guide CRISPR vector

  KN204264BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001136493, NM_001287808, NM_001287809, NM_032793, NR_109896, NM_001349821, NM_001349822, NM_001349823
• UniProt ID: Q8NA29
• Synonyms: MCPH15; MFSD2; NLS1
• Summary: The protein encoded by this gene is a transmembrane protein and sodium-dependent lysophosphatidylcholine transporter. The encoded protein is involved in the establishment of the blood-brain barrier and is required for brain growth and function. Defects in this gene are a cause of a progressive microcephaly syndrome. [provided by RefSeq, Mar 2017]
• Shipping: Ambient