MFSD2A Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: Human thyroid cancer, mouse liver and human fetal liver tissue, A549 and 293T cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MFSD2A |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 60 kDa |
| Gene Name | major facilitator superfamily domain containing 2A |
| Database Link | |
| Background | MFSD2 (major facilitator superfamily domain containing 2), also known as MFSD2A, is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. |
| Synonyms | MCPH15; MFSD2; NLS1 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Zhang, Schekman
Elife (2023) 12 DOI: 10.7554/eLife.84391
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