ERK1 (MAPK3) Human Gene Knockout Kit (CRISPR)

SKU
KN204196BN
MAPK3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ERK1
Locus ID 5595
Components

KN204196G1, ERK1 gRNA vector 1 in pCas-Guide CRISPR vector

KN204196G2, ERK1 gRNA vector 2 in pCas-Guide CRISPR vector

KN204196BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001040056, NM_001109891, NM_002746
UniProt ID P27361
Synonyms ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3
Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. provided by RefSeq, Jul 2008
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Other Versions
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GA103785 MAPK3 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase 3 1 kit
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KN204196 MAPK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204196LP MAPK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204196RB MAPK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404196 MAPK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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