OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

ERK1 (MAPK3) Mouse Monoclonal Antibody [Clone ID: OTI4D7]

  • Product Brand Image
Be the first to review this product
SKU
TA505700
MAPK3 (ERK1) mouse monoclonal antibody, clone OTI4D7 (formerly 4D7)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

Frequently Bought Together (3)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY400968 Transient overexpression lysate of mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP304196 Recombinant protein of human mitogen-activated protein kinase 3 (MAPK3), transcript variant 1, 20 µg
20 ug
$737.00

View other "ERK1 or NM_002746" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4D7
Application IF, IHC, WB
Recommended Dilution WB 1:200~2000, IHC 1:150, IF 1:100
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAPK3(NP_002737) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 43 kDa
Gene Name mitogen-activated protein kinase 3
Database Link
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. provided by RefSeq
Synonyms ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3
Reference Data
Protein Categories Enzyme: Kinases, Growth Factors, Intracellular Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adherens junction, Alzheimer's disease, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Non-small cell lung cancer, Oocyte meiosis, Pancreatic cancer, Pathways in cancer, Prion diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, TGF-beta signaling pathway, Thyroid cancer, Toll-like receptor signaling pathway, Type II diabetes mellitus, Vascular smooth muscle contraction, VEGF signaling pathway
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "OTI4D7" antibodies (4)
SKU Description Size Price
CF505700 Carrier-free (BSA/glycerol-free) MAPK3 mouse monoclonal antibody, clone OTI4D7 (formerly 4D7) 100 ug
$620.00
TA505700AM MAPK3 mouse monoclonal antibody,clone 4D7, Biotinylated 100 ul
$509.00
TA505700BM MAPK3 mouse monoclonal antibody,clone 4D7, HRP conjugated 100 ul
$509.00
TA505700S MAPK3 (ERK1) mouse monoclonal antibody, clone OTI4D7 (formerly 4D7) 30 ul
$200.00

file-alt Citations

The Elevated ASK1 Expression Inhibits Proliferation and Invasion in Gastric Cancer HGC-27 Cells
Wan, Shi, Ma et al
Anat Rec (Hoboken) (2018)
AI Summary: OriGene contributed mouse anti-human monoclonal antibodies against ASK1, p-p38, p38, p-JNK, JNK, p-ERK, ERK, and GAPDH, which were used in Western blot experiments to analyze signaling protein expression in the study.
Snippet: min. The primary antibodies (mouse anti- human monoclonal antibody ASK1/p-p38/p38/p-JNK/JNK p-ERK/ERK/GAPDH, ORIGENE) were added into block- ing solution and incubated with the membranes at 4 C overnight. The
WB
The Kinase Activity-deficient Isoform of Araf Antagonizes Ras/MAPK Signaling in the Zebrafish Embryo
Xiong, Liu, Meng
J. Biol. Chem. (2015)
AI Summary: In this study, the anti-ERK1 antibody from OriGene was used to detect ERK1 protein levels, contributing to the analysis of MAPK pathway activity in zebrafish embryos.
Snippet: The used primary antibodies were: anti-Myc and anti-HA from Santa Cruz;anti-Flag from Sigma;anti-Smad2/3 ， anti-phospho-Smad2 （ Ser465/467 ） and anti-phospho-ERK1/2 (Thr202/Tyr204) from Cell Signaling Technology;anti-ERK1 from OriGene;... Cite SaveSaving
WB
Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities
Mayer, Haigl, Jantscher et al
Cell Mol Life Sci (2010) 67 (19), 3299-311 DOI: 10.1007/s00018-010-0379-6
Cited by 20
AI Summary: In this study, OriGene’s Sprouty2 cDNA clone (Cat# RC208552) and Sprouty4 cDNA clone (Cat# RC221083) were used to investigate the cell cycle-dependent expression patterns of Sprouty2 and Sprouty4, enabling the authors to elucidate the regulatory mechanisms controlling Sprouty2 abundance.
Showing 1-3 of 3 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products