HDGF Human Gene Knockout Kit (CRISPR)

SKU KN204148BN

HDGF - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: HDGF
• Locus ID: 3068
• Components:

  KN204148G1, HDGF gRNA vector 1 in pCas-Guide CRISPR vector

  KN204148G2, HDGF gRNA vector 2 in pCas-Guide CRISPR vector

  KN204148BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001126050, NM_001126051, NM_001319186, NM_001319187, NM_001319188, NM_004494, NR_135008
• UniProt ID: P51858
• Synonyms: HMG1L2
• Summary: This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016]
• Shipping: Ambient