Nrf2 (NFE2L2) Human Gene Knockout Kit (CRISPR)

SKU
KN204140BN
NFE2L2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Nrf2
Locus ID 4780
Components

KN204140G1, Nrf2 gRNA vector 1 in pCas-Guide CRISPR vector

KN204140G2, Nrf2 gRNA vector 2 in pCas-Guide CRISPR vector

KN204140BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001145412, NM_001145413, NM_001313900, NM_001313901, NM_001313902, NM_001313903, NM_001313904, NM_006164
UniProt ID Q16236
Synonyms NRF2
Summary This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. provided by RefSeq, Sep 2015
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Other Versions
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GA103187 NFE2L2 CRISPRa kit - CRISPR gene activation of human nuclear factor, erythroid 2 like 2 1 kit
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KN204140 NFE2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN204140LP NFE2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN204140RB NFE2L2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN404140 NFE2L2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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