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CYP1B1 Human Gene Knockout Kit (CRISPR)

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SKU
KN204074RB
CYP1B1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CYP1B1 or NM_000104"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol CYP1B1
Locus ID 1545
Components

KN204074G1, CYP1B1 gRNA vector 1 in pCas-Guide CRISPR vector

KN204074G2, CYP1B1 gRNA vector 2 in pCas-Guide CRISPR vector

KN204074RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000104
UniProt ID Q16678
Synonyms CP1B; CYPIB1; GLC3A; P4501B1
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. provided by RefSeq, Jul 2008
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Resources
Other Versions
SKU Description Size Price
GA101092 CYP1B1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 1 subfamily B member 1 1 kit
$1,657.00
KN204074 CYP1B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204074BN CYP1B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204074LP CYP1B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404074 CYP1B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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