PACS1 Human Gene Knockout Kit (CRISPR)

SKU
KN204036BN
PACS1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PACS1
Locus ID 55690
Components

KN204036G1, PACS1 gRNA vector 1 in pCas-Guide CRISPR vector

KN204036G2, PACS1 gRNA vector 2 in pCas-Guide CRISPR vector

KN204036BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_018026, NM_178178
UniProt ID Q6VY07
Synonyms MRD17
Summary This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA110885 PACS1 CRISPRa kit - CRISPR gene activation of human phosphofurin acidic cluster sorting protein 1 1 kit
$1,657.00
KN204036 PACS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204036LP PACS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204036RB PACS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404036 PACS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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