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PACS1 Rabbit Polyclonal Antibody

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SKU
TA349175
Rabbit Polyclonal Anti-PACS1 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification PACS1 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 106 kDa; Observed: 105 kDa
Gene Name phosphofurin acidic cluster sorting protein 1
Database Link
Background The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).
Synonyms hfzo1; hfzo2
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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