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GGCX Human Gene Knockout Kit (CRISPR)

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SKU
KN204003LP
GGCX - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "GGCX or NM_000821"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol GGCX
Locus ID 2677
Components

KN204003G1, GGCX gRNA vector 1 in pCas-Guide CRISPR vector

KN204003G2, GGCX gRNA vector 2 in pCas-Guide CRISPR vector

KN204003LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000821, NM_001142269, NM_001311312
UniProt ID P38435
Synonyms VKCFD1
Summary This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015
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Other Versions
SKU Description Size Price
GA101789 GGCX CRISPRa kit - CRISPR gene activation of human gamma-glutamyl carboxylase 1 kit
$1,657.00
KN204003 GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204003BN GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204003RB GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404003 GGCX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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