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Human GGCX activation kit by CRISPRa

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SKU
GA101789
GGCX CRISPRa kit - CRISPR gene activation of human gamma-glutamyl carboxylase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350014 Rabbit Polyclonal Anti-GGCX Antibody
100 ul
$205.00
RC204003 GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 1
10 ug
$694.00

Other products for "GGCX"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GGCX
Locus ID 2677
Components

GA101789G1, GGCX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101789G2, GGCX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101789G3, GGCX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000821, NM_001142269, NM_001311312
UniProt ID P38435
Synonyms VKCFD1
Summary This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN204003 GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204003BN GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204003LP GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204003RB GGCX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404003 GGCX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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