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CAMKK2 Human Gene Knockout Kit (CRISPR)

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SKU
KN203468BN
CAMKK2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CAMKK2 or NM_001270485"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol CAMKK2
Locus ID 10645
Components

KN203468G1, CAMKK2 gRNA vector 1 in pCas-Guide CRISPR vector

KN203468G2, CAMKK2 gRNA vector 2 in pCas-Guide CRISPR vector

KN203468BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001270485, NM_001270486, NM_006549, NM_153499, NM_153500, NM_172214, NM_172215, NM_172216, NM_172226
UniProt ID Q96RR4
Synonyms CAMKK; CAMKKB
Summary The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. provided by RefSeq, Jul 2012
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Documents
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Other Versions
SKU Description Size Price
GA107295 CAMKK2 CRISPRa kit - CRISPR gene activation of human calcium/calmodulin dependent protein kinase kinase 2 1 kit
$1,657.00
KN203468 CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203468LP CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203468RB CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403468 CAMKK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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