Human CAMKK2 activation kit by CRISPRa

SKU
GA107295
CAMKK2 CRISPRa kit - CRISPR gene activation of human calcium/calmodulin dependent protein kinase kinase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CAMKK2
Locus ID 10645
Components

GA107295G1, CAMKK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107295G2, CAMKK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107295G3, CAMKK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001270485, NM_001270486, NM_006549, NM_153499, NM_153500, NM_172214, NM_172215, NM_172216, NM_172226
UniProt ID Q96RR4
Synonyms CAMKK; CAMKKB
Summary The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. provided by RefSeq, Jul 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN203468 CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203468BN CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203468LP CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203468RB CAMKK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403468 CAMKK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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