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Lin28 (LIN28A) Human Gene Knockout Kit (CRISPR)

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SKU
KN203397RB
LIN28A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA324388 LIN28A Antibody (Center)
400 ul
$645.00
RC203397 LIN28A (Myc-DDK-tagged)-Human lin-28 homolog A (LIN28A)
10 ug
$300.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "Lin28 or NM_024674"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Lin28
Locus ID 79727
Components

KN203397G1, Lin28 gRNA vector 1 in pCas-Guide CRISPR vector

KN203397G2, Lin28 gRNA vector 2 in pCas-Guide CRISPR vector

KN203397RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_024674
UniProt ID Q9H9Z2
Synonyms CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
GA112581 LIN28A CRISPRa kit - CRISPR gene activation of human lin-28 homolog A 1 kit
$1,657.00
KN203397 LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203397BN LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203397LP LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403397 LIN28A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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