Human Lin28 (LIN28A) activation kit by CRISPRa

SKU
GA112581
LIN28A CRISPRa kit - CRISPR gene activation of human lin-28 homolog A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LIN28A
Locus ID 79727
Components

GA112581G1, Lin28 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112581G2, Lin28 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112581G3, Lin28 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_024674
UniProt ID Q9H9Z2
Synonyms CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
KN203397 LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203397BN LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203397LP LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203397RB LIN28A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403397 LIN28A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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