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NKG2A (KLRC1) Human Gene Knockout Kit (CRISPR)

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SKU
KN203062RB
KLRC1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "NKG2A or NM_001304448"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol NKG2A
Locus ID 3821
Components

KN203062G1, NKG2A gRNA vector 1 in pCas-Guide CRISPR vector

KN203062G2, NKG2A gRNA vector 2 in pCas-Guide CRISPR vector

KN203062RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001304448, NM_002259, NM_007328, NM_213657, NM_213658
UniProt ID P26715
Synonyms CD159A; NKG2; NKG2A
Summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jan 2015
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Documents
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Other Versions
SKU Description Size Price
GA102590 KLRC1 CRISPRa kit - CRISPR gene activation of human killer cell lectin like receptor C1 1 kit
$1,657.00
KN203062 KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203062BN KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203062LP KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403062 KLRC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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