Human NKG2A (KLRC1) activation kit by CRISPRa

SKU
GA102590
KLRC1 CRISPRa kit - CRISPR gene activation of human killer cell lectin like receptor C1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KLRC1
Locus ID 3821
Components

GA102590G1, NKG2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102590G2, NKG2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102590G3, NKG2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001304448, NM_002259, NM_007328, NM_213657, NM_213658
UniProt ID P26715
Synonyms CD159A; NKG2; NKG2A
Summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jan 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN203062 KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203062BN KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203062LP KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203062RB KLRC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403062 KLRC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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