Ube1L (UBA7) Human Gene Knockout Kit (CRISPR)

SKU
KN202883RB
UBA7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Ube1L
Locus ID 7318
Components

KN202883G1, Ube1L gRNA vector 1 in pCas-Guide CRISPR vector

KN202883G2, Ube1L gRNA vector 2 in pCas-Guide CRISPR vector

KN202883RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003335
UniProt ID P41226
Synonyms D8; UBA1B; UBE1L; UBE2
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA105038 UBA7 CRISPRa kit - CRISPR gene activation of human ubiquitin like modifier activating enzyme 7 1 kit
$1,657.00
KN202883 UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202883BN UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202883LP UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402883 UBA7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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