Human Ube1L (UBA7) activation kit by CRISPRa

SKU
GA105038
UBA7 CRISPRa kit - CRISPR gene activation of human ubiquitin like modifier activating enzyme 7
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UBA7
Locus ID 7318
Components

GA105038G1, Ube1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105038G2, Ube1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105038G3, Ube1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003335
UniProt ID P41226
Synonyms D8; UBA1B; UBE1L; UBE2
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN202883 UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202883BN UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202883LP UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202883RB UBA7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402883 UBA7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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