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TTF1 (NKX2-1) Human Gene Knockout Kit (CRISPR)

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SKU
KN202477LP
NKX2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "TTF1 or NM_001079668"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol TTF1
Locus ID 7080
Components

KN202477G1, TTF1 gRNA vector 1 in pCas-Guide CRISPR vector

KN202477G2, TTF1 gRNA vector 2 in pCas-Guide CRISPR vector

KN202477LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001079668, NM_003317
UniProt ID P43699
Synonyms BCH; BHC; NK-2; NKX2.1; NKX2A; TEBP; TITF1; TTF-1; TTF1
Summary This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. provided by RefSeq, Feb 2014
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Other Versions
SKU Description Size Price
GA104883 NKX2-1 CRISPRa kit - CRISPR gene activation of human NK2 homeobox 1 1 kit
$1,657.00
KN202477 NKX2-1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202477BN NKX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202477RB NKX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402477 NKX2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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