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CD44 Human Gene Knockout Kit (CRISPR)

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SKU
KN202455LP
CD44 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CD44 or NM_000610"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CD44
Locus ID 960
Components

KN202455G1, CD44 gRNA vector 1 in pCas-Guide CRISPR vector

KN202455G2, CD44 gRNA vector 2 in pCas-Guide CRISPR vector

KN202455LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000610, NM_001001389, NM_001001390, NM_001001391, NM_001001392, NM_001202555, NM_001202556, NM_001202557
UniProt ID P16070
Synonyms CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
Summary The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA100682 CD44 CRISPRa kit - CRISPR gene activation of human CD44 molecule (Indian blood group) 1 kit
$1,657.00
KN202455 CD44 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202455BN CD44 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202455RB CD44 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402455 CD44 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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