CD44 Mouse Monoclonal Antibody [Clone ID: OTI1D8]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1D8 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD44(NP_000601) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | CD44 molecule (Indian blood group) |
| Database Link | |
| Background | The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. provided by RefSeq, Jul 2008 |
| Synonyms | CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1D8" antibodies (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506726 | Carrier-free (BSA/glycerol-free) CD44 mouse monoclonal antibody, clone OTI1D8 (formerly 1D8) | 100 ug |
$620.00
|
|
| TA506726AM | CD44 mouse monoclonal antibody, clone OTI1D8 (formerly 1D8), Biotinylated | 100 ul |
$509.00
|
|
| TA506726BM | CD44 mouse monoclonal antibody, clone OTI1D8 (formerly 1D8), HRP conjugated | 100 ul |
$509.00
|
|
| TA506726S | CD44 mouse monoclonal antibody, clone OTI1D8 (formerly 1D8) | 30 ul |
$200.00
|
|
| TA600542 | purified CD44 mouse monoclonal capture antibody, validated for Luminex assays | 100 ug |
$458.00
|
|
| TA700544 | purified CD44 biotinylated mouse monoclonal detection antibody, validated for Luminex assays | 50 ug |
$494.00
|
|
Citations
Enhanced Hyaluronan Signaling and Autophagy Dysfunction by VPS35 D620N
Rahman, Soto-Avellaneda, Yong Jin et al
Neuroscience (2020) 441, 33-45 DOI: 10.1016/j.neuroscience.2020.06.009
Rahman, Soto-Avellaneda, Yong Jin et al
Neuroscience (2020) 441, 33-45 DOI: 10.1016/j.neuroscience.2020.06.009
Cited by 17
AI Summary: In this study, the OriGene CD44 antibody (cat# TA506726) was used to detect CD44 protein levels, enabling the investigation of hyaluronan signaling and its role in autophagy dysfunction associated with the VPS35 D620N mutation in Parkinson’s disease models.
Snippet: cat# NB100-2220, Novus Biologicals), VPS35 (1:1000, cat# GTX108058, GeneTex), VPS29 (1:500, cat# ab10160, Abcam), VPS26 (1:500, cat# ab23892, Abcam), V5 (1:1000, cat# 13202S, Cell Signaling Technology), CD44 (1:200, cat# TA506726, Origene), phospho;Primary antibodies were used to detect LC3 (1:1000, cat# NB100-2220, Novus Biologicals), VPS35 (1:1000, cat# GTX108058, GeneTex), VPS29 (1:500, cat# ab10160, Abcam), VPS26 (1:500, cat# ab23892, Abcam), V5 (1:1000, cat# 13202S, Cell Signaling Technology), CD44 (1:200, cat# TA506726, Origene), phospho-AKT (Ser 473) (1:1000, cat# 4060, Cell Signaling Technology), HMMR (1:1000, cat# GTX54121, Genetex), WASH1 (1:500, cat# NBP1-90464, Novus Biologicals) and β-actin (1:2000, cat# MA1-91399, Thermo Fisher)
T-Box20 inhibits osteogenic differentiation in adipose-derived human mesenchymal stem cells: the role of T-Box20 on osteogenesis
Mollazadeh, Fazly Bazzaz, Neshati et al
J Biol Res (Thessalon) (2019) 26, 8 DOI: 10.1186/s40709-019-0099-5
Mollazadeh, Fazly Bazzaz, Neshati et al
J Biol Res (Thessalon) (2019) 26, 8 DOI: 10.1186/s40709-019-0099-5
AI Summary: OriGene’s human TBX20 cDNA clone (Cat# RC223307) was used in this study to overexpress Tbx20 in adipose-derived human mesenchymal stem cells, enabling the authors to investigate its inhibitory effect on osteogenic differentiation.
Snippet: osciences, San Jose, CA) following immunostaining for cell surface antigens at passage three. Mouse monoclonal antibodies directed against CD11b, CD34, CD44, CD45, CD90, and CD105 were purchased from Acris Antibodies (Herford, Germany). FITC-conjugated goat anti-mouse antibodies were obtained from Biolegend (San Diego, CA). To induce osteogenic differentiation, cells were kept in basal medium con
Investigating Autophagy Dysfunction Induced by a Parkinson's Disease-Causing Mutation in VPS35
Rahman
Thesis (2018)
Rahman
Thesis (2018)
Snippet: … INVESTIGATING AUTOPHAGY DYSFUNCTION INDUCED BY A PARKINSON'S DISEASE-CAUSING MUTATION IN VPS35 by Abir Ashfakur Rahman A dissertation submitted in partial fulfillment of the requirements for the degree of;Primary antibodies were used to detect LC3 (Novus Biologicals, NB100-2220), CD44 (Origene, TA506726), Phospho-AKT (Ser 473) (Cell Signaling, 4060), RHAMM (Genetex, GTX54121) and βactin (Thermo Fisher, MA1-91399)
Showing 1-3 of 3 papers.
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