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TMS1 (PYCARD) Human Gene Knockout Kit (CRISPR)

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SKU
KN202409BN
PYCARD - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "TMS1 or NM_013258"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TMS1
Locus ID 29108
Components

KN202409G1, TMS1 gRNA vector 1 in pCas-Guide CRISPR vector

KN202409G2, TMS1 gRNA vector 2 in pCas-Guide CRISPR vector

KN202409BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_013258, NM_145182, NM_145183
UniProt ID Q9ULZ3
Synonyms ASC; CARD5; TMS; TMS-1; TMS1
Summary This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA109241 PYCARD CRISPRa kit - CRISPR gene activation of human PYD and CARD domain containing 1 kit
$1,657.00
KN202409 PYCARD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202409LP PYCARD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202409RB PYCARD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402409 PYCARD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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