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UBP43 (USP18) Human Gene Knockout Kit (CRISPR)

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SKU
KN202374BN
USP18 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "UBP43 or NM_017414"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol UBP43
Locus ID 11274
Components

KN202374G1, UBP43 gRNA vector 1 in pCas-Guide CRISPR vector

KN202374G2, UBP43 gRNA vector 2 in pCas-Guide CRISPR vector

KN202374BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_017414
UniProt ID Q9UMW8
Synonyms ISG43; UBP43
Summary The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
GA107769 USP18 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 18 1 kit
$1,657.00
KN202374 USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202374LP USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202374RB USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402374 USP18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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