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Human UBP43 (USP18) activation kit by CRISPRa

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SKU
GA107769
USP18 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 18
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA383147 USP18 Rabbit polyclonal Antibody
100 ul
$410.00
RC202374 USP18 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 18 (USP18)
10 ug
$457.00

Other products for "USP18"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol USP18
Locus ID 11274
Components

GA107769G1, UBP43 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107769G2, UBP43 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107769G3, UBP43 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_017414
UniProt ID Q9UMW8
Synonyms ISG43; UBP43
Summary The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN202374 USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202374BN USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202374LP USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202374RB USP18 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402374 USP18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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